摘要:To improve the treatment effect in the pharmaceutical wastewater in the biochemical system, the experiment domesticated efficient aerobic activated sludge to deal with wastewater deeply. In the presence of glucose co-matrix, indole was used as the characteristic pollutant to acclimate aerobic activated sludge by increasing pollutant concentration. The degradation characteristics and microbial characteristics during training were studied. The experimental results showed that indole could inhibit the growth of microorganisms in activated sludge, but after 2 months of intensive culture, activated sludge could adapt to the environment in which indole was the only carbon source. The bacteria species in the sludge were mainly Comamonas (34.18%) and Aci- netobacter (15.45%), which could treat indole with a concentration of 200mg/L, the degradation efficiency was increased from 80% to more than 98.6%, and the SOUR value was stable at more than 7.61 mgO_2/g MLSS・h, which was suitable for application in advanced treatment engineering of indole-containing pharmaceutical wastewater.