Along with the rapid development of the Yellow River delta’s economy, the contradiction between population, environment, and resource is highlighted, the land problem has more and more influence to the human survival, and the sustainable use of the land becomes necessary for the coordination and getting along with the human and the natural environment. Based on the land information, we analysis and simulate the sustainable development of the Yellow River delta area. By analysis the system structure of land use and the relationship between each subsystem, we construct a dynamic model of regional sustainable development based on land information. Then put the yellow triangle area of Binzhou city as a case to simulate the development models under different constraint conditions of land use. Using the principle of system dynamics to simulate the dynamic change of land using under study area, account for the regional sustainable development system, quantify the influence from the land using change on the sustainable development of the yellow triangle area, and predict the evolution trend of studying regional land using in the future.