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  • 标题:Exact prior-free probabilistic inference on the heritability coefficient in a linear mixed model
  • 本地全文:下载
  • 作者:Qianshun Cheng ; Xu Gao ; Ryan Martin
  • 期刊名称:Electronic Journal of Statistics
  • 印刷版ISSN:1935-7524
  • 出版年度:2014
  • 卷号:8
  • 期号:2
  • 页码:3062-3076
  • DOI:10.1214/15-EJS984
  • 语种:English
  • 出版社:Institute of Mathematical Statistics
  • 摘要:Linear mixed-effect models with two variance components are often used when variability comes from two sources. In genetics applications, variation in observed traits can be attributed to biological and environmental effects, and the heritability coefficient is a fundamental quantity that measures the proportion of total variability due to the biological effect. We propose a new inferential model approach which yields exact prior-free probabilistic inference on the heritability coefficient. In particular we construct exact confidence intervals and demonstrate numerically our method’s efficiency compared to that of existing methods.
  • 关键词:Differential equation;inferential model;plausi bility;unbalanced design;variance components.
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