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  • 标题:Biomolecular signal tracker with fast time response. ⁎
  • 本地全文:下载
  • 作者:H. De Battista ; J. Picó ; E. Picó-Marco
  • 期刊名称:IFAC PapersOnLine
  • 印刷版ISSN:2405-8963
  • 出版年度:2019
  • 卷号:52
  • 期号:26
  • 页码:1-6
  • DOI:10.1016/j.ifacol.2019.12.227
  • 语种:English
  • 出版社:Elsevier
  • 摘要:Signal tracking and the related signal derivative estimation are key pieces in feedback control engineered systems. In this work we present a synthetic biomolecular circuit that performs signal tracking with high precision under mild conditions on its parameters. The circuit contains two antithetic motifs in feedback via a push-pull switch motif. We show that the output signal quickly converges to the input one. Under ideal conditions, finite-time convergence would be achieved. We also show that the circuit gives a good approximation of the input signal derivative.
  • 关键词:KeywordsBiological circuitsSynthetic biologyDifferentiatorBiomolecular trackerAntithetic motif
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