摘要:Schizophrenia is a psychotic disorder (or a group of disorders) marked by the serious impairment of thought, emotionsandbehavior. Most schizophrenics, if not treated, gradually withdraw from interactions with other people, and lose the ability to takecare of personal needs and care.The use of estrogen as a potential treatment for schizophrenia opens new opportunities for both preventive treatment and acutetreatment of schizophrenia in men and women. There are still considerable studies to be made to determine the correct dose andduration of estradiol use for its safe use in women and men with schizophrenia in terms of known side effects and whether it caneventually be used as an independent drug, as an adjuvant.The results of the studies provided strong evidence for the estrogen protection hypothesis, and the addition of transdermalestradiol was associated with a significant reduction in psychotic symptoms in patients with DSM-IV schizophrenia compared tostandardized treatment with antipsychotic drugs.The physiotherapist, as a member of an interdisciplinary team, through the exercise program that he provided, improved thephysical mental health of patients. Physiotherapists are experts in physical health, which provide an important step between physicaland mental health in patients with schizophrenia.