摘要:This study aims to determine the antimicrobial activities, total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) of the medicinal mushroom Phellinus igniarius (L.) Quel, and P. rimosus (Berk.). Within this scope, mushroom samples were subjected to extraction in a Soxhlet extractor. Antimicrobial activity were tested using the agar dilution method against Staphylococcus aureus ATCC 29213, S. aureus MRSA ATCC 43300, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Acinetobacter baumannii ATCC 19606, Candida albicans ATCC 10231, C. krusei ATCC 34135 ATCC 13803, and C. glabrata. TAS, TOS and OSI values were determined using Rel Assay kits. As a result of the study, it was found that extracts of P. igniarius and P. rimosus had antimicrobial effect at 50-400 (pg/mL) concentrations. Moreover, it was found that P. igniarius had a higher TAS value. P. rimosus also had higher TOS and OSI values. Consequently, it is thought that P. igniarius and P. rimosus have antioxidant and antimicrobial potential, and these mushrooms can be used as natural sources in pharmacological research.