摘要:AbstractPurposePhyto-active components ofZanthoxylum zanthoxyloides and Gongronema latifoliumwas investigated against microbial contaminants in water for possible novel antimicrobial usage in water treatment.MethodCrude ethyl acetate and chloroform fractions ofZanthoxylum zanthoxyloides and Gongronema latifoliumwere prepared and screened for antimicrobial and phytochemical profiles using standard methods.ResultsCrude extracts of the different plant examined selectively comprised saponins, tannins, reducing sugars, anthraquinones, flavonoids, terpenoids, phlobatanins and alkaloids. All plant extracts showed broad spectrum antibiosis againstE. coli,P. aeruginosa,Klebsiellasp,S. pneumoniaeandB. cereus, as well asA. niger, A. flavus, Trichoderma sp and Candidasp. Chloroform extracts compared well than ethyl acetate extracts.ConclusionThis work represents the first report to direct the possible application ofZanthoxylum zanthoxyloides and Gongronema latifoliumto potential application in water. Overall results revealed that antimicrobial activities are dose and plant dependent. Noteworthy is the comparatively greater antimicrobial activity of crude extracts over commercial antibiotics used at the concentration of extracts tested. These plants can therefore serve as a potent source of natural water disinfectant.