摘要：This paper represents comparative phenolic contents and antioxidant activity of available Mikania species (family-Asteraceae) in Bangladesh with folkloric reputation. These species are Mikania cordata (MC), Mikania micrantha (MM) and Mikania scandens (MS). The ethanolic extract (70%) of the selected plants were tested for total phenolics (TPC), total flavonoids (TFC), total antioxidant capacity (TAC), ferrous reducing capacity (FRC), DPPH free radical scavenging assay (DRSA), hydroxyl radical scavenging activity (HRSA) and hydrogen peroxide Assay (HPSA). The TPC of MC, MM and MS were 456.3±0.08, 271.2±0.80 and 168.1±0.83 mg of gallic acid equivalent/g of dry extract and TFC were 672.8±0.76, 349.5±0.97 and 152.8±0.76 mg of catechin equivalent/g of dry extract, respectively. The data indicated that MC contained higher amount of TPC and TFC followed by MM and MS. The TAC and FRC were in the following order: MC> MM>MS. In DRSA, the IC50 of MC was 11.50 μg/mL which was comparable to standard ascorbic acid (10.01 μg/mL) followed by MM (19.76 μg/mL) and MS (36.39 µg/mL). Same results were observed for HRSA and HPA where MC showed the most potent inhibitory activity. The TPC of MC was also positively correlated (p< 0.001) with DFSA, HRSA and HPSA. The findings conclude that Mikania cordata possesses highest antioxidative phytochemicals compare to others available mikania species, justifying the frequency of use in traditional folk medicine in Bangladesh compared to other species.
关键词：Mikania cordata; M. micrantha; M. scandens; Asteraceae; Antioxidant; Polyphenols
