摘要：Highlights•Children may be more sensitive to environmental exposures at critical periods.•The association between green space and insulin resistance in youth is unclear.•We assessed sensitive life-periods of exposure to green space and HOMA-IR in youth.•Early life exposure to green space was not associated with HOMA-IR in youth.•Associations did not differ across sex, race/ethnicity or socioeconomic status.AbstractBackgroundRecent studies suggest that greater exposure to natural vegetation, or “green space” is associated with lower diabetes risk, possibly through increasing physical activity. However, there is limited research on green space and insulin resistance in youth. We hypothesized greater green space at early-life sensitive time periods would be associated with lower insulin resistance in youth.MethodsWe used data from Project Viva (N = 460), a pre-birth cohort study that recruited pregnant women in eastern Massachusetts, 1999–2002, and followed offspring into adolescence. We defined residential green space exposure at infancy (median age − 1.1 years), early childhood (3.2 years), mid-childhood (7.7 years), and early adolescence (12.8 years), using 30 m resolution Landsat satellite imagery to estimate the Normalized Difference Vegetation Index [NDVI
关键词：Longitudinal data;Green space;Environmental epidemiology;Insulin resistance;Sensitive periods;Children’s health
