摘要：Highlights•Exposure to residential green space is associated with decreased risk of PTB.•Green space has stronger protective associations with PTB in the second trimester.•There are positive interactions between green space and air pollution on PTB.AbstractBackgroundRecent studies have reported inconsistent associations between maternal residential green space and preterm birth (PTB, born ObjectivesTo evaluate the relationships between green space and PTB, identify windows of susceptibility, and explore potential interactions between green space and air pollution.MethodsBirth certificate records for all births in California (2001–2008) were obtained. The Normalized Difference Vegetation Index (NDVI) was used to characterized green space exposure. Gestational age was treated as a time-to-event outcome; Cox proportional hazard models were applied to estimate the association between green space exposure and PTB, moderately PTB (MPTB, gestational age 2.5), nitrogen dioxide (NO2), and ozone (O3)
关键词：Preterm birth;Green space;Air pollution;Interaction;Exposure time window
