摘要：AbstractAn efficient, eco-friendly and sustainable approach for the synthesis of novel spiroindeno[1,2-b]quinoxaline-3-phenylspiro[4,3″]benzylidenepiperidone ring system has been developed by a one-pot four component [3 + 2] cycloaddition strategy. The 1,3-dipole generatedin situfrom quinoxalinone andl-phenylalanine reacts with the highly functionalized dipolarophiles, bisarylidene piperidones affording spirohybrid heterocycles in good yields. The unexplored novel class of dispirohybrid heterocycles obtained possess three CN and two CC bonds with four adjacent stereogenic carbons, out of which two is spirocarbons. The structure of compounds was elucidated using1H,13C and mass spectroscopic studies.
