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  • 标题:Tannins: An Antinutrient with Positive Effect to Manage Diabetes
  • 本地全文:下载
  • 作者:M. Kumari ; S. Jain
  • 期刊名称:Research Journal of Recent Sciences
  • 电子版ISSN:2277-2502
  • 出版年度:2012
  • 卷号:1
  • 期号:12
  • 页码:70-73
  • 语种:English
  • 出版社:International Science Community Association
  • 摘要:Plant tannins, including hydrolysable and condensed varieties, are well known antioxidants in medicinal plants, foods, and edible fruits. Phenolic compounds and flavonoids are a unique category of plant phytochemicals especially in terms of their vast potential health-benefiting properties. Tannins are potential antioxidants. They have been considered to be cardio-protective, anti-inflammatory, anti-carcinogenic and anti-mutagenic, among others. Tannins enhance glucose uptake and inhibit adipogenesis, thus being potential drugs for the treatment of NIDDM.Tannins can improve the pathological oxidativestate of a diabetic situation. Many earlier studies suggested that phenolic compounds and flavonoids protect against many types of cancer. In particular, phenolic compounds have been reported to modulate intracellular signalling through PI3K and p38 MAPK pathways, modulating the activity of target enzymes and modulating gene expression. Condensed Tannins have a wide range of biological and pharmacological activities including antioxidative, cardio-protective, antitumor, antibacterial, antiviral, anti-inflammatory and immune-modulatory. These specific phytochemicals provide a promising area of research for future human studies and potential nutraceutical for disease prevention and treatment.
  • 关键词:Tannin;phenol;phytochemicals;antioxidants;nutraceutical
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