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  • 标题:Role of Proteus mirabilis in Caffeine Degradation–A Preliminary Bioinformatics Study
  • 本地全文:下载
  • 作者:Thangaraj Naina ; Siddharth Sharan ; Suneetha Vuppu
  • 期刊名称:Research Journal of Recent Sciences
  • 电子版ISSN:2277-2502
  • 出版年度:2013
  • 卷号:2
  • 页码:33-40
  • 语种:English
  • 出版社:International Science Community Association
  • 摘要:An attempt to find the role of Proteus mirabilis in caffeine degradation using bioinformatics tools has been made here. Soils from coffee industries were taken and the bacterium was isolated and found to degrade caffeine. Identification of the bacterium through Sangers dideoxy sequencing of 16S rDNA was done and its genome taken from online database was used for homology modeling of the enzyme to identify regions of similarity and enzyme structure prediction. Also attempts to secondary structure prediction and protein threading has been done to study the enzyme and compare the enzymes of Proteus mirabilis with that of other reported caffeine degrading organisms.
  • 关键词:Caffeine degradation;bioinformatics;homology modeling;protein threading;secondary structure prediction
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