标题：Green biosynthesis of silver nanoparticle using Commiphora myrrh extract and evaluation of their antimicrobial activity and colon cancer cells viability
摘要：Graphical abstractDisplay OmittedHighlights•The synthesized AgNPs showed good stability, and no visible changes were observed even after 4 months.•AgNPs were characterized by TEM, FTIR, Zetasizer, and UV–vis spectral analysis.•Applications of AgNPs using myrrh aqueous extract have more promising results in colon cancer and antimicrobial activities against several pathogenic micro.AbstractThere is increasing attention directed to mineral nanoparticle for intensive applications in various fields of science, such as medicine, chemistry, agriculture, and biotechnology. There is also a growing attentiveness to the use of eco-friendly methods to synthesize nanoparticle without making or using environmentally dangerous substances to human health. This article describes the biological methods for green synthesis usingCommiphora myrrhasilver nanoparticle (AgNP) extract. C. myrrha-synthesized AgNPs, which were completed by exposing myrrh aqueous extract to silver nitrate, were characterized by transmission electron microscopy, Fourier transform infrared spectroscopy, Zetasizer, and ultraviolet–visible spectral analyses. AgNPs were characterized by varying the color of the solution from light yellow to brown and then depicting the surface plasmon-resonance peaks at 445 nm. This study has promising results in the treatment of colon cancer, as it has impressive outcomes using different concentrations of AgNPs in 100 μl medium (30%) compared to control (100%). The results also showed increasing inhibition zones of antibacterial activity with AgNPs inEnterococcus faecalis(59 mm) andBacillus cereus(51 mm) compared to myrrh aqueous extract. Fungi that were screened for growth inhibition zones were Fusarium oxysporum (20 mm),Alternaria alternata(14 mm), andTrichoderma(10 mm).
