摘要:Athletes receive training to improve physiology functions that can improve VO2 max, but training intensively leads to oxidative stress . Maltodextrin and vitamin C are nutrient which can suppress increasing of malondialdehyde (MDA) a marker of oxidative stress . The aim of this study was to assess effect of maltodextrin and vitamin C combination drink on MDA level in soccer athletes. Type of this study was experimental with same subject design. The study was conducted from January until June 2014 at Culinary Laboratory Universitas Gadjah Mada (UGM), Stadium of Universitas Negeri Yogyakarta (UNY) and Laboratory of Biochemistry UGM. Subjects of this study were 14 soccer athletes coming from UNY. Every subject had to meet the inclusion and exclusion criteria and was choosen by purposive sampling. In the first treatment subjects received maltodextrin and vitamin C combination drink. After six days wash out period, subjects received 300 mL plain water. Drinks were given 30 min before and five minutes after VO2 max test continued by physical exercise. Malondialdehyde was measured using thiobarbit uric acid (TBA) method and was performed in 30 min after exercise. Malondialdehyde level, when athletes consume maltodextrin and vitamin C combination drink, was significantly lower than malondialdehyde level when athletes consume plain water (p = 0.0003). Maltodextrin and vitamin C combination drink is more effective to reduce malondialdehyde than plain water.