摘要:Biosensors play a key role in medical diagnostics, and acoustic wave technology such as solidly mounted resonators (SMRs) applied to this field is one of the latest developments with great potential. This study seeks to explore the potential application of SMRs to detect and quantify prostate-specific antigen (PSA) for the screening and diagnosis of prostate cancer. The primary results show promising frequency shift of SMR sensors coated with Polydimethylsiloxane (PDMS) to different liquids. The SMR frequency is 1.082, 1.084 and 1.088 GHz, respectively, to air, deionized water and toluene (liquid) presence. These sensors have great potential as an accurate, low-cost method for measuring PSA and biomarkers for cancer and other diseases.