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  • 标题:Ficus pumila L. improves the prognosis of patients infected with HTLV-1, an RNA virus
  • 本地全文:下载
  • 作者:Kenji Gonda ; Koichi Suzuki ; Yumi Sunabe
  • 期刊名称:Nutrition Journal
  • 印刷版ISSN:1475-2891
  • 电子版ISSN:1475-2891
  • 出版年度:2021
  • 卷号:20
  • DOI:10.1186/s12937-021-00672-x
  • 语种:English
  • 出版社:BioMed Central
  • 摘要:Human T-cell leukemia virus type 1 was isolated as the retrovirus to be identified in humans. Here, we focused on Ficus pumila L. as a factor that be effective against human T-cell leukemia virus type 1. The significant and novel findings is that symptoms of patients with drinking Ficus pumila L. extracts did not worsen despite a lack of aggressive pharmacotherapy against adult T-cell leukemia, a human T-cell leukemia virus type 1-associated myelopathy, or T-cell leukemia virus type 1 uveitis. Twenty-eight of the 194 inpatients who underwent showed high levels of human T-cell leukemia virus type 1. Among human T-cell leukemia virus type 1-infected patients, those who were administered Ficus pumila L. extracts had no human T-cell leukemia virus type 1-related symptoms, while those who were not administered Ficus pumila L. extracts had human T-cell leukemia virus type 1-related diseases and a significantly poorer prognosis. This suggests that the Ficus pumila L. extracts may show some utility against virus infection.
  • 关键词:Ficus pumila L.; HTLV-1; miRNA; Ooitabi
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