期刊名称：IOP Conference Series: Earth and Environmental Science
印刷版ISSN：1755-1307
电子版ISSN：1755-1315
出版年度：2020
卷号：421
期号：3
DOI：10.1088/1755-1315/421/3/032029
语种：English
出版社：IOP Publishing
摘要：Preparations based on humic acids are widely used in veterinary practice, as they are based on raw materials of natural origin. The environmental toxicity of the drug based on humic substances "Gumi drinking" was assessed by biotesting using test objects of different taxonomic groups. As a result of the research in the acute and subacute experiment on Tetrahymena pyriformis W. LD50=575,1±1,01 mg/ml, in a chronic experiment the maximum inactive dose was 10−1 mg/ml. When assessing the impact of "Gumi drinking" on the germination of seeds of crops such as radishes, oats, cucumbers, the effects of inhibition of development were noted: ET (radish) = 1,35%, ET (cucumber) = 0,13%, ET (oat) = 0,66%. Studies using the test object Eisenia foetida for 14 days found that the survival rate was 100%, reducing the columellar weight did not occur. In the study of embryotoxicity on the eggs of Lymnaea stagnalis L. a dose dependent effect of inhibition of shellfish hatching under the action of solutions in different concentrations was revealed. "Gumi drinking" in single-day guppies at exposure of 96 hours at a concentration of 500 mg/d on the 4th day of the experiment caused the death of 3.4% of fry. The effect of the drug on earthworms Nicodrilus caliginosus and coprophages did not have a negative impact. Thus, "Gumi drinking" can be attributed to non-toxic substances according to the degree of danger to the environment.
