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  • 标题:Pre-existing conditions in Hispanics/Latinxs that are COVID-19 risk factors
  • 本地全文:下载
  • 作者:Timothy S. Chang ; Yi Ding ; Malika K. Freund
  • 期刊名称:iScience
  • 印刷版ISSN:2589-0042
  • 出版年度:2021
  • 卷号:24
  • 期号:3
  • 页码:1-24
  • DOI:10.1016/j.isci.2021.102188
  • 语种:English
  • 出版社:Elsevier
  • 摘要:SummaryCoronavirus disease 2019 (COVID-19) has exposed health care disparities in minority groups including Hispanics/Latinxs (HL). Studies of COVID-19 risk factors for HL have relied on county-level data. We investigated COVID-19 risk factors in HL using individual-level, electronic health records in a Los Angeles health system between March 9, 2020, and August 31, 2020. Of 9,287 HL tested for SARS-CoV-2, 562 were positive. HL constituted an increasing percentage of all COVID-19 positive individuals as disease severity escalated. Multiple risk factors identified in Non-Hispanic/Latinx whites (NHL-W), like renal disease, also conveyed risk in HL. Pre-existing nonrheumatic mitral valve disorder was a risk factor for HL hospitalization but not for NHL-W COVID-19 or HL influenza hospitalization, suggesting it may be a specific HL COVID-19 risk. Admission laboratory values also suggested that HL presented with a greater inflammatory response. COVID-19 risk factors for HL can help guide equitable government policies and identify at-risk populations.Graphical abstractDisplay OmittedHighlights•Hispanics/Latinxs (HL) had worse COVID-19 outcomes than Non-HL whites (NHL-W)•The worse HL outcomes remained after correcting for common comorbid risk factors•Most risk factors were shared, but mitral valve disorder was only a risk in HL•Hospitalized HL presented with a greater inflammatory responsePublic health; virology
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