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  • 标题:Chikungunya virus outbreak expansion and microevolutionary events affecting epidemiology and epidemic potential
  • 本地全文:下载
  • 作者:Ann M Powers
  • 期刊名称:Research and Reports in Tropical Medicine
  • 印刷版ISSN:1179-7282
  • 电子版ISSN:1179-7282
  • 出版年度:2015
  • 卷号:6
  • 页码:11-19
  • DOI:10.2147/RRTM.S53698
  • 出版社:Dove Medical Press Ltd
  • 摘要:Chikungunya virus (CHIKV) is a mosquito-borne virus that is associated with severe and prolonged arthralgia. Starting in 2004, CHIKV reemerged in a series of outbreaks along the east coast of Africa and on several islands of the Indian Ocean. Over the subsequent 10 years, the virus spread throughout the globe and caused over three million cases. Molecular characterization of the genomes over time revealed changes that were associated with changes in epidemiology and transmission patterns. Monitoring and exploitation of these changes may lead to better understanding of viral movement and potential options for prevention and control.
  • 关键词:chikungunya; alphaviral evolution; molecular epidemiology; transmission; outbreaks
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