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  • 标题:Mitochondria-targeted antioxidant protects against irradiation-induced salivary gland hypofunction
  • 本地全文:下载
  • 作者:Xibao Liu ; Krishna P. Subedi ; Changyu Zheng
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • DOI:10.1038/s41598-021-86927-3
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:A severe consequence of radiation therapy in patients with head and neck cancer is persistent salivary gland hypofunction which causes xerostomia and oral infections. We previously showed that irradiation (IR) of salivary glands in mice triggers initial transient increases in mitochondrial reactive oxygen species (ROS mt), mitochondrial [Ca 2+
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