标题：Comparative effect of papaya ( Carica papaya) leaves’ extract and Toltrazuril on growth performance, hematological parameter, and protozoal load in Sonali chickens infected by mixed Eimeria spp.
期刊名称：Journal of Advanced Veterinary and Animal Research
印刷版ISSN：2311-7710
出版年度：2021
卷号：8
期号：1
页码：91-100
DOI：10.5455/javar.2021.h490
语种：English
出版社：Bangladesh Agricultural University, Faculty of Veterinary Science
摘要：Objective:
Anticoccidial drugs may lead to the development of drug resistance and drug residues. Herbal extracts could be an attractive alternative. This research was undertaken to evaluate the anticoccidial outcome of
Carica papaya compared with the anticoccidial drug (Toltazuril) in Sonali chickens.
Materials and Methods:
A total of 80 Sonali chickens were evenly and equally allocated into four groups, namely
T
1 (non-infected control),
T
2 (infected control),
T
3 (treated with
C. papaya), and
T
4 (treated with Toltrazuril). All groups were experimentally infected with oocysts of mixed
Eimeriaspp. orally except
T
1, and the mixed
Eimeriaspp. oocyst load (OL), body weight (BW) gain, and hematological parameters were calculated.
Results:
In the findings, the highest OL reduction rate in
T
4 was 100%, while the
T
3 was 83.44%. Nevertheless, BW differed significantly (
p < 0.01) among the different groups, while the daily BW gain was higher in
T
3 amounting to 8.10 gm. In the case of hematological parameter, total erythrocyte count (TEC), hemoglobin (Hb), packed cell volume (PCV), and erythrocyte sedimentation rate in different groups were almost the same and were also statistically insignificant (
p > 0.05) barring total leukocyte count resulting as significant (
p < 0.05) at day 30. Additionally, the results of Pearson’s correlation in
T
3 at day 30 indicated a strong significant (
p < 0.01) negative correlation between OL and BW (
r = −0.780) with the following regression equation:
y = −0.16*
x + 433.665. Moreover, the correlation of TEC, PCV, and Hb with OL was significantly (
p < 0.01) negative,
r = −0.786,
r = −0.752 and
r = −0.633, where the regression equations were
y = −0.03*
x + 4.51,
y = −0.03*
x + 27.42, and
y = −0.04*
x + 11.40, respectively.
Conclusion:
Long-term use of
C. papaya leaves’ extracts effectively controls coccidiosis in Sonali chickens and can act as an effective growth promoter.
