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  • 标题:The molecular activation and regulation mechanisms of proteolytic Toll signaling cascade in insect innate immunity
  • 本地全文:下载
  • 作者:K H Ryu ; J W Park ; K Kurokawa
  • 期刊名称:Invertebrate Survival Journal
  • 电子版ISSN:1824-307X
  • 出版年度:2010
  • 卷号:7
  • 期号:2
  • 页码:181-191
  • 语种:English
  • 出版社:Universita degli Studi di Modena e Reggio Emilia
  • 摘要:Recently we biochemically determined the molecular recognition and regulatory mechanisms of how beetle’s larvae recognize Gram-positive bacteria and fungi via Toll signaling cascade. The biochemical analysis of newly identified molecules provides us how beetles recognize invading pathogenic microbes and how they defend their bodies using elegant innate immunity. Here, we will focus on reviewing the biochemical analyses and biological functions of newly identified molecules involved in insect Toll signaling cascade.
  • 关键词:Toll cascade;innate immunity;protease inhibitor;insects
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