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  • 标题:Effect of intraoperative fluid volume on postoperative ileus after robot-assisted radical cystectomy
  • 本地全文:下载
  • 作者:Ji Sung Shim ; Tae Il Noh ; Ja Hyeon Ku
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • DOI:10.1038/s41598-021-89806-z
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:This study aimed to investigate the effect of intraoperative fluid volume on the postoperative ileus (POI) recovery period. A retrospective review of the Korean robot-assisted radical cystectomy database identified 718 patients who underwent robot-assisted radical cystectomy (RARC). Regression analyses were performed to identify the associations between the amount of intraoperative fluid administration (crystalloid/colloid/total), POI period (time to flatus/bowel movements), and length of hospital stay (LOS) after adjusting for covariates. In addition, we analyzed the risk factors for gastrointestinal complications and prolonged POI using a logistic regression model. An increasing volume of the administered crystalloid/total fluid was associated with prolonged POI (crystalloid R 2  = 0.0725 and P < 0.0001; total amount R 2  = 0.0812 and P < 0.0001), and the total fluid volume was positively associated with the LOS (R 2  = 0.099 and P < 0.0001). The crystalloid amount was a risk factor for prolonged POI (P < 0.001; odds ratio, 1.361; 95% confidence interval, 1.133–1.641; P < 0.001). In the context of RARC, increased intravenous fluids are associated with prolonged POI and longer LOS.
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