首页    期刊浏览 2024年12月05日 星期四
登录注册

文章基本信息

  • 标题:Toxic action of substances from male fern Dryopteris filix-mas (L.) Schott (1834) on free-living soil nematode Caenorhabditis elegans Maupas (1900)
  • 本地全文:下载
  • 作者:Anastasia Egorova ; Alsu Gatiyatullina ; Dmitriy Terenzhev
  • 期刊名称:E3S Web of Conferences
  • 印刷版ISSN:2267-1242
  • 电子版ISSN:2267-1242
  • 出版年度:2021
  • 卷号:254
  • 页码:1-7
  • DOI:10.1051/e3sconf/202125409011
  • 语种:English
  • 出版社:EDP Sciences
  • 摘要:The study of biological activity of extracts from roots and rhizomes of male fernDryopteris filix-maswas carried out in experiments with soil nematodeCaenorhabditis elegans. The toxicity of extracts ofD. filix-masroots and rhizomes obtained by different methods varied over a wide range. Crude extract of male fern roots and rhizomes in concentration range 62.5–250 µg/ml had a weak toxic action onC. elegansorganism by inducing death of 26.0–43.3% nematodes. The toxicity of relatively high concentrations (500 and 250 µg/ml) of water-ethanolic extracts might be compared with such of crude extract in concentrations 62.5–250 µg/ml. Biological activity of filicinic acids ethers was found very high: concentrations of crude extract ofD. filix-masroots and rhizomes and concentrations of filicinic acids ethers with similar toxicity forC. elegansorganism were 40-fold different. Substances isolated fromD. filix-masroots and rhizomes have nematicidal activity and may be used for development of drugs to treat helminthiasis of humans and animals.
国家哲学社会科学文献中心版权所有