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  • 标题:CARDIOVASCULAR RESPONSES TO STONEFISH SYNANCEIA VERRUCOSA VENOM IN BALB/C MICE
  • 本地全文:下载
  • 作者:Mohammad Wahsha ; Haya Al-Tarawneh ; MaroofKhalaf
  • 期刊名称:Fresenius Environmental Bulletin
  • 印刷版ISSN:1018-4619
  • 出版年度:2021
  • 卷号:30
  • 期号:2
  • 页码:891-898
  • 语种:English
  • 出版社:PSP Publishing
  • 摘要:Stonefish samples (Synanceia verrucosa) werecollected along the coastline of the Gulf of Aqaba,Red Sea.The acute toxicity of the extracted venomon BALB/c mice was evaluated using the bio-chemical assays: Lipid Peroxidation (LPO),AlanineTransaminase (ALT), Gamma-Glutamyl Transferase (GGT),and Lactate Dehydrogenase(LDH).Results showed that when mice are injectedintramuscularly with 0.107mg venom/kg,the venominduces a significant increase in lipid peroxidationlevels andaseriesofhistopathologicalcharacteristics,such assevere inflammation,haemorrhage,andcellular degeneration incardiovascular tissue.Moreover,enzymaticactivities were evaluated.Significant increases inALT,GGT,and LDH activities were found due tocellular injuries caused by the stonefish venom.
  • 关键词:Synanceia verrucosa;Gulf of Aqaba;Stonefish;Red sea;Toxicity
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