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  • 标题:DNA DAMAGES OF WIDELY USED PESTICIDES; A COMET ASSAY REPORT FOR CHLOROTHALONIL AND GLYPHOSATE POTASSIUM SALT
  • 本地全文:下载
  • 作者:Dilek Asci Celik ; Vehbi Atahan Togay ; Gulcin Yavuz Turel
  • 期刊名称:Fresenius Environmental Bulletin
  • 印刷版ISSN:1018-4619
  • 出版年度:2021
  • 卷号:30
  • 期号:4A
  • 页码:4170-4176
  • 语种:English
  • 出版社:PSP Publishing
  • 摘要:The aim of the study was to determine the gen-otoxicity of chlorothalonil and glyphosate potassium salt.Increasing use of these pesticides makes it necessary to determine their possible adverse effects on humans.Chlorothalonil and glyphosate potassium salt were administered in three different concentrations (Glyphosate potassium salt: 0.6 mg/L,0.12 mg/L,0.24 mg/L; Chlorothalonil: 0.03 mg/L,0.06 mg/L,0.15 mg/L) to human lymphocytes.An alkaline comet assay was conducted and T ail DNA Percentage parameter was chosen to demonstrate DNA Damage.According to our results,glyphosate potassium salt has a considerably harmful effect on geno-toxicity.DNA damage was significantly higher in all glyphosate potassium salt groups when compared to the control group.Chlorothalonil,which is generally considered to be genotoxic,did not cause any significant DNA damage.
  • 关键词:Chlorothalonil;Comet assay;DNA Damage;Glyphosate;Glyphosate potassium salt;Pesticide.
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