摘要：HYPERTHYROIDISM IS CAUSED BY A THYROID-STIMULATING HORMONE (TSH) RECEPTOR THAT STIMULATES AUTOANTIBODIES THAT CAUSE EXCESS PRODUCTION AND GROWTH OF THYROID HORMONES.HYPERTHYROIDISM IN CHILDHOOD IS OFTEN CAUSED BY GRAVES-BASEDOW DISEASE.APART FROM CASES OF TRANSIENT NEONATAL HYPERTHYROIDISM THAT DEVELOP FROM MOTHERS WITH ACTIVE GRAVES-BASEDOW DISEASE, HYPERTHYROIDISM OCCURS LESS IN PRESCHOOL CHILDREN AND RARELY IN CHILDHOOD.SYMPTOMS OF HYPERTHYROIDISM INCLUDE EXCESS PHYSICAL ACTIVITY, TREMOR, TACHYCARDIA, FLUSHING, PALPITATIONS, WEIGHT LOSS, ACCELERATED LINEAR GROWTH, REDUCED BONE MINERALIZATION, AND POOR SCHOOL PERFORMANCE.IN CHILDHOOD GRAVES’ DISEASE, OPHTALMOPATHY OCCURS IN LESS THAN 50 PERCENT OF PATIENTS AND IS USUALLY MILD WHEN PRESENT.WE'RE PRESENTING THE CASE OF A 2,8 YEARS OLD GIRL WITH BASEOW-GRAVES DISEASE HOSPITALIZED FOR BILATERAL EXOPHTHALMIA.SHORTLY AFTER THE FIRST YEAR, THE BABY GIRL DEVELOPED SIGNS OF HYPERTHYROIDISM, BUT THE MOTHER NEGLECTED THE PRESENTATION TO THE DOCTOR.THE MOST PROMINENT FEATURES WERE THE ACCELERATION OF SKELETAL MATURATION, LINEAR GROWTH AND CHARACTERISTIC APPEARANCE OF THE FACE.LATE MANIFESTATIONS WERE REVERSIBLE FOLLOWING TREATMENT WITH ANTITHYROID SYNTHESIS.
