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  • 标题:Programmed cell death and its role in inflammation
  • 本地全文:下载
  • 作者:Yong Yang ; Gening Jiang ; Peng Zhang
  • 期刊名称:Military Medical Research
  • 印刷版ISSN:2054-9369
  • 出版年度:2015
  • 卷号:2
  • 期号:1
  • 页码:12
  • DOI:10.1186/s40779-015-0039-0
  • 语种:English
  • 出版社:BioMed Central
  • 摘要:Cell death plays an important role in the regulation of inflammation and may be the result of inflammation. The maintenance of tissue homeostasis necessitates both the recognition and removal of invading microbial pathogens as well as the clearance of dying cells. In the past few decades, emerging knowledge on cell death and inflammation has enriched our molecular understanding of the signaling pathways that mediate various programs of cell death and multiple types of inflammatory responses. This review provides an overview of the major types of cell death related to inflammation. Modification of cell death pathways is likely to be a logical therapeutic target for inflammatory diseases.
  • 关键词:Inflammation ; Necroptosis ; Apoptosis ; Pyroptosis ; Pyronecrosis ; NETosis ; Autophagy
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