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  • 标题:PB01 suppresses radio-resistance by regulating ATR signaling in human non-small-cell lung cancer cells
  • 本地全文:下载
  • 作者:Tae Woo Kim ; Da-Won Hong ; Sung Hee Hong
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • DOI:10.1038/s41598-021-91716-z
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:Despite the common usage of radiotherapy for the treatment of human non-small-cell lung cancer (NSCLC), cancer therapeutic efficacy and outcome with ionizing radiation remains a challenge. Here, we report the antitumor effects and mechanism of a novel benzothiazole derivative PB01 (4-methoxy-cyclohexane carboxylic acid [2-(3,5-dimethyl-isoxazole-4-yl) sulpanil-benzothiazole-6-yl
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