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  • 标题:Modular barcode beads for microfluidic single cell genomics
  • 本地全文:下载
  • 作者:Cyrille L. Delley ; Adam R. Abate
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • DOI:10.1038/s41598-021-90255-x
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:Barcode beads allow efficient nucleic acid tagging in single cell genomics. Current barcode designs, however, are fabricated with a particular application in mind. Repurposing to novel targets, or altering to add additional targets as information is obtained is possible but the result is suboptimal. Here, we describe a modular framework that simplifies generation of multifunctional beads and allows their easy extension to new targets.
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