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  • 标题:A binge high sucrose diet provokes systemic and cerebral inflammation in rats without inducing obesity
  • 本地全文:下载
  • 作者:Omkar L. Patkar ; Abdalla Z. Mohamed ; Ashwin Narayanan
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • DOI:10.1038/s41598-021-90817-z
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:While the dire cardiometabolic consequences of the hypercaloric modern ‘Western’ diet are well known, there is not much information on the health impact of a high sucrose diet not inducing weight gain. Here, we tested the hypothesis that rats reared with intermittent binge access to sucrose in addition to normal chow would develop an inflammatory response in brain. To test this hypothesis, we undertook serial PET/MRI scans with the TSPO ligand [ 18F
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