首页    期刊浏览 2024年11月28日 星期四
登录注册

文章基本信息

  • 标题:First theoretical determination of relative biological effectiveness of very high energy electrons
  • 本地全文:下载
  • 作者:Rachel Delorme ; Thongchai A. M. Masilela ; Camille Etoh
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • DOI:10.1038/s41598-021-90805-3
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:Very high energy electrons (VHEEs, E > 70 MeV) present promising clinical advantages over conventional beams due to their increased range, improved penumbra and relative insensitivity to tissue heterogeneities. They have recently garnered additional interest in their application to spatially fractionated radiotherapy or ultra-high dose rate (FLASH) therapy. However, the lack of radiobiological data limits their rapid development. This study aims to provide numerical biologically-relevant information by characterizing VHEE beams (100 and 300 MeV) against better-known beams (clinical energy electrons, photons, protons, carbon and neon ions). Their macro- and microdosimetric properties were compared, using the dose-averaged linear energy transfer ( \documentclass[12pt
国家哲学社会科学文献中心版权所有