摘要:SummaryRecent advancements in bidimensional nanoparticles production such as graphene (G) and graphene oxide (GO) have the potential to meet the need for highly functional personal protective equipment (PPE) against SARS-CoV-2 infection. The ability of G and GO to interact with microorganisms provides an opportunity to develop engineered textiles for use in PPE and limit the spread of COVID-19. PPE in current use in high-risk settings for COVID transmission provides only a physical barrier that decreases infection likelihood and does not inactivate the virus. Here, we show that virus pre-incubation with soluble GO inhibits SARS-CoV-2 infection of VERO cells. Furthermore, when G/GO-functionalized polyurethane or cotton was in contact SARS-CoV-2, the infectivity of the fabric was nearly completely inhibited. The findings presented here constitute an important innovative nanomaterial-based strategy to significantly increase PPE efficacy in protection against the SARS-CoV-2 virus that may implement water filtration, air purification, and diagnostics methods.Graphical abstractDisplay OmittedHighlights•Graphene oxide (GO) traps Sars-CoV-2 particles in liquid medium•Cotton or polyurethane can be functionalized with graphene or GO nanoparticles•Infection is inhibited when Sars-CoV-2 contacts with functionalized fabrics•Graphene-functionalized fabrics are effective against bacteria and are biocompatibleHealth sciences; Public health; Disease; Materials science; Nanostructure