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  • 标题:Graphene nanoplatelet and graphene oxide functionalization of face mask materials inhibits infectivity of trapped SARS-CoV-2
  • 本地全文:下载
  • 作者:Flavio De Maio ; Valentina Palmieri ; Gabriele Babini
  • 期刊名称:iScience
  • 印刷版ISSN:2589-0042
  • 出版年度:2021
  • 卷号:24
  • 期号:7
  • 页码:1-15
  • DOI:10.1016/j.isci.2021.102788
  • 语种:English
  • 出版社:Elsevier
  • 摘要:SummaryRecent advancements in bidimensional nanoparticles production such as graphene (G) and graphene oxide (GO) have the potential to meet the need for highly functional personal protective equipment (PPE) against SARS-CoV-2 infection. The ability of G and GO to interact with microorganisms provides an opportunity to develop engineered textiles for use in PPE and limit the spread of COVID-19. PPE in current use in high-risk settings for COVID transmission provides only a physical barrier that decreases infection likelihood and does not inactivate the virus. Here, we show that virus pre-incubation with soluble GO inhibits SARS-CoV-2 infection of VERO cells. Furthermore, when G/GO-functionalized polyurethane or cotton was in contact SARS-CoV-2, the infectivity of the fabric was nearly completely inhibited. The findings presented here constitute an important innovative nanomaterial-based strategy to significantly increase PPE efficacy in protection against the SARS-CoV-2 virus that may implement water filtration, air purification, and diagnostics methods.Graphical abstractDisplay OmittedHighlights•Graphene oxide (GO) traps Sars-CoV-2 particles in liquid medium•Cotton or polyurethane can be functionalized with graphene or GO nanoparticles•Infection is inhibited when Sars-CoV-2 contacts with functionalized fabrics•Graphene-functionalized fabrics are effective against bacteria and are biocompatibleHealth sciences; Public health; Disease; Materials science; Nanostructure
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