摘要：SummaryLong-lived organisms are exposed to the risk of accumulating mutations due to DNA damage. Previous studies in animals have revealed the positive relationship between the copy number of DNA repair genes and longevity. However, the role of DNA repair in the lifespan of plants remains poorly understood. Using the recent accumulation of the complete genome sequences of diverse plant species, we performed systematic comparative analyses of the copy number variations of DNA repair genes in 61 plant species with different lifespans. Among 121 DNA repair gene families,PARPgene family was identified as a unique gene that exhibits significant expansion in trees compared to annual and perennial herbs. Among three paralogs of plantPARPs,PARP1showed a close association with growth rate. PARPs catalyze poly(ADP-ribosyl)ation and play pivotal roles in DNA repair and antipathogen defense. Our study suggests the conserved role of PARPs in longevity between plants and animals.Graphical abstractDisplay OmittedHighlights•Comparing the copy number variations of DNA repair genes in diverse plant species•PARPgene family showed higher copy number in trees compared to herbs•There was negative correlation between copy number ofPARP1and growth rate in trees•Increased copy number ofPARPwould be evolutionary favored in plant longevityBiological sciences; Phylogenetics; Plant genetics; Plant biology
