摘要:Recent studies have demonstrated that social isolation during the 2020 COVID–19 pandemic has significantly impacted the mental and physical health of people worldwide. However, it remains unknown whether physical activity can improve mental health in a state of emergency. The present study aimed to examine the importance of physical exercising and stress management mechanisms (problem-focused, emotion-focused, and avoidant) in the context of mental health indicators (depression, anxiety, and nonspecific stress) in conditions of social isolation during COVID–19-induced lockdown in Serbia. The sample consisted of 680 adults (66% female), mean aged 35.91 years (SD = 12.45). The results indicated a significant relation between physical exercising and a reduced stress response and confirmed the usefulness of the already well-known problem-focused strategies. Avoidant and emotionfocused coping were associated with poorer mental health outcomes. However, as a moderator, physical activity lowered anxiety levels in individuals prone to emotion-focused coping.