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  • 标题:Volitional Weight-Lifting in Rats Promotes Adaptation via Performance and Muscle Morphology prior to Gains in Muscle Mass
  • 本地全文:下载
  • 作者:Erik P. Rader ; G. Roger Miller ; Robert D. Chetlin
  • 期刊名称:Environmental Health Insights
  • 电子版ISSN:1178-6302
  • 出版年度:2014
  • 卷号:2014
  • 期号:Suppl. 1
  • 页码:1-9
  • DOI:10.4137/EHI.S15257
  • 语种:English
  • 出版社:Libertas Academica
  • 摘要:

    Investigation of volitional animal models of resistance training has been instrumental in our understanding of adaptive training. However, these studies have lacked reactive force measurements, a precise performance measure, and morphological analysis at a distinct phase of training – when initial strength gains precede muscle hypertrophy. Our aim was to expose rats to one month of training (70 or 700 g load) on a custom-designed weight-lifting apparatus for analysis of reactive forces and muscle morphology prior to muscle hypertrophy. Exclusively following 700 g load training, forces increased by 21% whereas muscle masses remained unaltered. For soleus (SOL) and tibialis anterior (TA) muscles, 700 g load training increased muscle fiber number per unit area by ~20% and decreased muscle fiber area by ~20%. Additionally, number of muscle fibers per section increased by 18% for SOL muscles. These results establish that distinct morphological alterations accompany early strength gains in a volitional animal model of load-dependent adaptive resistance training.

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