摘要:The article substantiates provisions aimed at improving the tools for implementing the strategy of sustainable spatial development of the Russian Federation, taking into account the processes of systemic digital transformation of the economy. The aim of the study is to substantiate a new methodological approach to the interpretation of the patterns of sustainable regional development, which considers the spatial and environmental factors as endogenous sources of sustainable growth. To achieve this goal, the stages of development of ideas about the regional economy and regional development were determined, the content of the spatial approach to the interpretation of economic phenomena and processes was clarified, recommendations were formulated aimed at improving the toolkit of regional policy, taking into account the structuredness and multipolarity of the Russian economic, environmental and information space. The result of the study is the conclusion about the heterogeneity of the space of Russian regions and the need to take into account environmental space quality indicators when developing program measures for sustainable development, as well as in assessing their effectiveness.