摘要：Prof. Kuo-Chen Chou was a highly cited researcher listed by Clarivate Analytics (2014-2018). He was a biophysicist, and bio informatician with numerous contributions to science, and has been Health's Honorary Editor-in-Chief. He was affiliated with the Gordon Life Science Institute, (a non-profit research organization in Boston that he founded) until his recent passing. A scientist who is a biophysicist, he studied the physical principles of living things and their biological processes on cell devel opment, growth, heredity, and disease; and his contribution towards this unique field is enhanced with his bioinformatics training, enabling scientists to better predict and study certain drug molecule binding within a protein. His significant progress was the use of graphical approaches to study biological problems to provide insights for analyzing complicated mechanisms, has generated a graphic rules proposed by him and his co-workers (widely known as Chou’s graphic rules), and is widely used, example in studying change in liver glucokinase in a non-steady-state, inhibition of HIV-1 reverse transcriptase, drug metabo lism systems. Prof. Chou's work has left a legacy that will be continued by younger scientists.
