摘要：Background
The study aimed to evaluate the long-term change of health-related quality of life (HRQOL) and to identify predictors of HRQOL 5 years after cardiac surgery.
Methods
Consecutive adult patients, undergoing elective cardiac surgery were enrolled in the study. HRQOL was measured using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) questionnaire before and 5-years after cardiac surgery. A multivariate latent change modeling approach was used for data analysis.
Results
210 participants (30.5% female) were reached at 5-year follow-up and included in final data analysis. The study revealed, after controlling for gender effects, a significant long-term positive change, in physical functioning (PF, M
slope
= 19.79,
p < 0.001), social functioning (SF, M
slope
= 17.27,
p < 0.001), vitality (VT, M
slope
= 6.309,
p < 0.001) and mental health (MH, M
slope
= 8.40,
p < .001) in the total sample. Lower education was associated with an increase in PF (M
slope
= 24.09,
p < 0.001) and VT (M
slope
= 8.39,
p < 0.001), more complicated surgery (other than the coronary artery bypass graft (CABG) predicted increase in general health (GH, M
slope
= 6.76,
p = 0.005). Arrhythmia was a significant predictor for lower pre- and post-operative VT and SF.
Conclusions
Overall HRQOL in our sample improved from baseline to five years postoperatively. Further studies including larger patient groups are needed to confirm these findings.
关键词：Cardiac surgery; Health-related quality of life; Risk factors; Long-term
