摘要：SummaryThe Laplace pressure is one of the most fundamental regulators that determine cell shape and function, and thus has been receiving widespread attention. Here, we systemically investigate the effect of the Laplace pressure on the shape and function of the cells during cytokinesis. We find that the Laplace pressure during cytokinesis can directly control the distribution and size of cell blebbing and adjust the symmetry of cell division by virtue of changing the characteristics of cell blebbing. Further, we demonstrate that the Laplace pressure changes the structural uniformity of cell boundary to regulate the symmetry of cell division. Our findings provide further insights as to the important role of the Laplace pressure in regulating the symmetry of cell division during cytokinesis.Graphical abstractDisplay OmittedHighlights•The Laplace pressure controls the distribution and size of cell blebbing•The Laplace pressure helps to develop a more uniform cell boundary•The Laplace pressure regulates symmetry of cell division by way of blebsCell; Functional aspects of cell biology; Biophysics
