摘要：Background:
Schools are often located near traffic sources, leading to high levels of exposure to traffic-related air pollutants, including black carbon (BC). Thus, the school environment could play in a significant role in the adverse respiratory health of children.
Objectives:
Our objective was to determine associations between personal BC levels at school and airway inflammation [i.e., fractional exhaled nitric oxide (FeNO)] in school-age children. We hypothesized that higher school BC (SBC) would be associated with higher FeNO.
Methods:
Children 9–14 years of age in New York City (NYC) (
n
=
114
) wore BC monitors for two 24-h periods over a 6-d sampling period, repeated 6 months later. SBC was defined as the average personal BC concentrations measured during NYC school hours (i.e., 0830–1430 hours). FeNO was measured following each 24-h BC monitoring period. Multivariable linear regression in generalized estimating equation models were used to examine associations between SBC and FeNO. Results are presented as percentage difference (PD) in FeNO.
Results:
Personal BC at school was associated with higher FeNO (
PD
=
7.47
%
higher FeNO per
1
-
μ
g
/
m
3
BC (95% CI: 1.31, 13.9),
p
=
0.02
]. Compared with BC exposure during school, a smaller PD in FeNO was observed in association with BC exposure while commuting to and from school [
PD
=
6.82
%
(95% CI: 0.70, 13.3),
p
=
0.03
]. Personal BC in non-school environments and residential BC were not associated with FeNO (
p
>
0.05
). A significant association between personal BC at school and FeNO was observed among children with seroatopy who did not have asthma [
PD
=
21.5
%
(95% CI: 4.81, 40.9),
p
=
0.01
].
Discussion:
Schools may be important sources of BC exposure that contribute to airway inflammation in school-age children. Our results provide rationale for interventions that target improved air quality in urban schools and classrooms.
https://doi.org/10.1289/EHP8985
