标题：Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation
摘要：Correction to:
Scientific Reports 10.1038/s41598-017-17999-3, published online 19 December 2017
This article contains errors in the Introduction, where
“
App
NL-G-F/NL-G-F mice carrying the homozygous mutant
App gene encoding the humanised Aβ sequence (G601R, F606Y, and R609H) with three pathogenic mutations, namely Swedish (KM595/596NL), Beyreuther/Iberian (I641F), and Arctic (E618G)
10, progressively exhibit Aβ accumulation starting at 4 to 6 months of age, dense distributions of microglia and astrocytes from 9 months of age, and behavioural symptoms from 8 to 12 months of age
10,11.”
should read:
“
App
NL-G-F/NL-G-F mice carrying the homozygous mutant
App gene encoding the humanised Aβ sequence (G676R, F681Y, and R684H) with three pathogenic mutations, namely Swedish (KM670/671NL), Beyreuther/Iberian (I716F), and Arctic (E693G)
10, progressively exhibit Aβ accumulation starting at 4 to 6 months of age, dense distributions of microglia and astrocytes from 9 months of age, and behavioural symptoms from 8 to 12 months of age
10,11.”
In addition, in the Methods section, under the subheading ‘Animals’,
“Heterozygous
App
+/NL-G-F mice carrying humanised Aβ sequence (G601R, F606Y, R609H), Swedish (ML595/596NL), Beyreuther/Iberian (I641F), and Arctic (E618G) mutations, were previously established
10.”
should read:
“Heterozygous
App
+/NL-G-F mice carrying humanised Aβ sequence (G676R, F681Y, R684H), Swedish (KM670/671NL), Beyreuther/Iberian (I716F), and Arctic (E693G) mutations, were previously established
10.”
