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  • 标题:PD-L1 expression, EGFR and KRAS mutations and survival among stage III unresected non-small cell lung cancer patients: a Danish cohort study
  • 本地全文:下载
  • 作者:Deirdre Cronin-Fenton ; Tapashi Dalvi ; Naimisha Movva
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • DOI:10.1038/s41598-021-96486-2
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:Programmed cell death receptor ligand-1 (PD-L1) expression, KRAS ( KRASm) and EGFR ( EGFRm) mutations may influence non-small cell lung cancer (NSCLC) prognosis. We aimed to evaluate PD-L1 expression, KRASm, and EGFRm and survival among stage III unresected NSCLC patients. Using Danish registries, we collected data on stage III unresected NSCLC patients diagnosed 2001–2012 and paraffin-embedded tumor tissue from pathology archives. We assessed PD-L1 expression in tumors and tumor-infiltrating immune cells (ICs) by immunohistochemistry ( \documentclass[12pt
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