期刊名称：Walailak Journal of Science and Technology (WJST)
印刷版ISSN：2228-835X
出版年度：2021
卷号：18
期号：16
页码：1-6
DOI：10.48048/wjst.2021.9564
语种：English
出版社：Institute of Research and Development, Walailak University.
摘要：Maesa Montana is a flowering plant of the Myrsinaceae family, which is locally known as ramjani. The current study aimed to evaluate the in-vitro anti-arthritic and anti-inflammatory activities of the root extract of this plant. The anti-inflammatory performances were measured by the hindrance of egg white denaturation, and anti-arthritic activity was investigated by Bovine serum protein. In the anti-inflammatory activity test, the methanolic root extract of this plant showed 69.29 ± 1.19 % of inhibition at a concentration of 1000 µg/mL and standard drug exhibited 90.11 ± 1.45 % of inhibition at the same concentration. Furthermore, in the anti-arthritic activity test, the extract demonstrated 68.18 ± 1.34 % of inhibition at a concentration of 1000 µg/mL whereas the standard diclofenac drug showed 90.65 ± 1.19 % of inhibition at the same concentration. These results revealed that the root extract of this plant possesses significant anti-arthritic and anti-inflammatory activities based on the inhibition of BSA and protein denaturation.HIGHLIGHTSMethanol soluble compounds extraction from the roots of Maesa MontanaAnti-inflammatory activity determination using egg albuminAnti-arthritic activity measurement using bovine serum albuminGRAPHICAL.
关键词：Maesa Montana; Anti-arthritic; Anti-inflammatory; Protein denaturation
