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  • 标题:Rumex hastatus derived silver nanoparticles development and their potential applications as hepatic-protection agent along with antimicrobial activity
  • 本地全文:下载
  • 作者:Hina Gul ; Falak Sher Khan ; Umara Afzal
  • 期刊名称:Journal of King Saud University - Science
  • 印刷版ISSN:1018-3647
  • 出版年度:2021
  • 卷号:33
  • 期号:7
  • 页码:1-8
  • DOI:10.1016/j.jksus.2021.101587
  • 语种:English
  • 出版社:Elsevier
  • 摘要:AbstractCurrent study aimed to develop eco-friendly and cost-effective approaches for silver nanoparticle (AgNPs) synthesis using leaf extract ofRumex hastatusand characterization using various analytical techniques. Besides, the crystallinity of Ag+, reduction/stability, functional groups and structural morphology were determined through X-ray diffraction (XRD), Fourier transforms infrared spectroscopy (FT-IR spectroscopy) and scanning electron microscopy (SEM) respectively. The biosynthesized RH-AgNPs were investigated for hepatoprotective and cytotoxic effect, antioxidative activities and antimicrobial potential. Results revealed that RH-AgNPs were effective against hepatotoxin (carbon tetrachloride) at all tested concentrations by exhibiting very valuable results; showed high antioxidant potential and cytotoxic effect against HepG2 cancer cell lines. RH-AgNPs showed very promising antibacterial results as well. Overall, these results highlighted the potential of RH-AgNPs to be used for the treatment of various diseases.
  • 关键词:Herbal plants;Rumex hastatus;Silver nanoparticles;Hepatoprotective activity;Cytotoxic activity;Antioxidant activity;Antibacterial activity
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