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  • 标题:Electrophoresis of Proteins in the Biochemistry Laboratory of the University Hospital of Brazzaville
  • 本地全文:下载
  • 作者:Fylla Koumou Onanga ; Jeanne Kibah Gambomi ; Monde Ikia
  • 期刊名称:Open Access Library Journal
  • 印刷版ISSN:2333-9705
  • 电子版ISSN:2333-9721
  • 出版年度:2021
  • 卷号:08
  • 期号:9
  • 页码:1-6
  • DOI:10.4236/oalib.1107902
  • 语种:English
  • 出版社:Scientific Research Pub
  • 摘要:Background and aim: The electrophoresis of serum proteins is one of the examinations requested at the Biochemistry laboratory, with a view to highlight various pathologies. The aim of our study is to analyze the different electrophoretic profiles encountered in our current practice. Methods: This is a retrospective study of 350 serum samples collected at the biochemistry laboratory of the University Hospital Center (CHU) of Brazzaville. The electrophoresis of serum proteins was carried out on a Minicap Flex Piercing machine from Sebia. Results: One hundred and ninety-five (195) sera from women and 155 sera from men were collected from patients aged 12 to 85 years. Ninety-one, or 26% of PSE were normal. Two hundred and fifty nine or 74% were pathological. Inflammation was noted in 194 (55%) of cases of which 145 (41%) were chronic and 49 (14%) acute. Forty-two (12%) of our patients had beta-gamma block and 11 (3%) others presented with nephrotic syndrome. Monoclonal peaks were observed in 12 patients (3%). Conclusion: This study highlights the plurality of different electrophoretic profiles, with a predominance of profiles emanating from the Gastro-Enterology department. It nevertheless reveals the question of relevance in the request for these examinations, since no clinical information is documented for the attention of the clinical practitioner.
  • 关键词:ElectrophoresisSerum ProteinsMinicapProtein Profiles
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