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  • 标题:Genetic effects on longitudinal cognitive decline during the early stages of Alzheimer’s disease
  • 本地全文:下载
  • 作者:Atul Kumar ; Maryam Shoai ; Sebastian Palmqvist
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • DOI:10.1038/s41598-021-99310-z
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:Cognitive decline in early-stage Alzheimer’s disease (AD) may depend on genetic variability. In the Swedish BioFINDER study, we used polygenic scores (PGS) (for AD, intelligence, and educational attainment) to predict longitudinal cognitive change (measured by mini-mental state examination (MMSE) [primary outcome
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