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  • 标题:Publisher Correction: Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19
  • 本地全文:下载
  • 作者:Martin A. Redhead ; C. David Owen ; Lennart Brewitz
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • DOI:10.1038/s41598-021-99041-1
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:Correction to: Scientific Reports 10.1038/s41598-021-92416-4, published online 24 June 2021 The original version of this Article contained errors in Table 1, where the molecules were incorrectly displayed. The original Table 1 and accompanying legend appear below. Table 1 Structure–activity relationship of 4-aminoquinazoline EGFR inhibitors against SARS-CoV-2 PL pro. Compound number Generic name R 1 R 2 R 3 R 4 R 5 IC 50 (µM) (range) 8 Tarloxotinib Br F N N 0.3 (0.1–0.5) 9 Tarloxotinib (ac) Br F N N 0.3 (0.1–0.4) 10 Pelitinib Cl Cl > 100* 11 Afatinib Cl Cl N 12 (11–16) 12 Dacomitinib Cl Cl N 4 (3–5) 13 Gefitinib Cl Cl N 7 (6–11) *The range could not be established due to lack of potency. The original Article has been corrected.
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