摘要:This study aims to explore the relationship between social support, meaning in life and depression, and further explore the mediating role of meaning in life between social support and depression. This survey of 287 university students were investigated with the short version of Center for Epidemiologic Studies Depression Scale (CES-D-13), the Social Support Rating Scale (SSRS), and the Chinese Meaning in Life Questionnaire (MLQ). The results showed that: (1)The junior is the most serious period of depressive symptoms(11.33±7.019), and also an important turning point; (2) Non-only-child (10.23±6.713) were significantly higher than the only-child (9.02±6.230) about depressive symptoms (p=0.0368); (3)The depression were significantly negatively correlated with social support (r=-0.35, p<0.01) and the meaning in life(r=0.39, p<0.01), but there was a significant negative correlation between the meaning in life and social support (r=0.28, p<0.01); (4) The meaning in life plays a partial mediating role between social supports and depressive symptoms in university students. This research provides theoretical evidence for the prevention and intervention of university students’ depression from two aspects of social support and meaning in life.